We integrate technology-development and systems approaches to study how RNA-protein interactions mechanistically regulate gene expression, and how disruption of these interactions drives cancer and neurological disease. We develop tools to probe RNA-binding and RNA-translation landscapes, to programmably target and modify RNA, and to map RNA binding protein (RBP) networks. We will use biological insights obtained using these tools to design, build and test RNA-based medicine.
Ricardo Antonio Noriega-Rivera, PhD
Vrutant Shah, PhD
Luiz Henrique de Santana Maniero